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F.A.Q. Section

Diprovate®-G Plus Cream

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Diprovate®-G Plus Cream

Diprovate®-G Plus Cream is a strong topical medication containing corticosteroid, antibiotic, and Zinc Sulfate. It is used to treat the variety of skin infections, as well as to relieve itching, pain, swelling, and irritation on the skin. Diprovate®-G Plus Cream is developed for use in adults and children over 13 years of age.

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Description

Diprovate®-G Plus Cream is a potent topical treatment manufactured by Avalon Pharma. It is used to cure infections of the skin, such as cellulitis and eczema among others, and relieve itching, swelling, pain, and other inflammatory symptoms. The active ingredients of Diprovate®-G Plus Cream are Betamethasone Dipropionate, Gentamicin, and Zinc Sulfate. Betamethasone Dipropionate is a synthetic corticosteroid of glucocorticoid class with immunosuppressive and anti-inflammatory properties. Gentamicin is a broad-spectrum antibiotic of aminoglycoside class. Zinc Sulphate in an inorganic hydrate essential for healthy cells growth.

Indications:

- itching, swelling, rash, and irritation caused by allergic reactions

- skin and skin structure infections (cellulitis, burn wound infection)

- minor bacterial skin infection (folliculitis, furunculosis, impetigo, eczema, pyoderma gangrenosum, sycosis barbae, infectious eczematoid dermatitis, pustular acne, pustular psoriasis, infected seborrheic dermatitis, infected contact dermatitis, and infected excoriations)

MOA (mechanism of action):

Betamethasone Dipropionate activates the inhibitory proteins of phospholipase A2 and prevents the release of inflammatory agents, including histamine, eicosanoids, prostaglandins, leukotrienes, and cytokines. With these actions, Betamethasone Dipropionate reduces autoimmune reactions and inflammation. It is found superior if used alongside topical Zinc Sulfate.

Gentamicin inhibits protein synthesis in bacteria binding to the bacterial 30S ribosomal subunit and causing misreading of t-RNA, therefore ruins infecting bacteria overgrowth.

Zink Sulphate has wound-healing, and soothing properties. It prevents the release of keratinocyte-associated inflammatory mediators and mast cells (also known as mastocytes or labrocytes) degranulation, thereby reducing the secretion of histamine, an essential inducer of itching. It also causes re-epithelialization of partial thickness wounds and second-degree burns.

Dosage

Diprovate®-G Plus Cream is for external use only. Do not apply to your eyes, mouth, inside of the nose, private parts, and any other mucosal surface.

For the face: Apply Diprovate®-G Plus Cream 3-4 times daily for 5 days. Consult your doctor regarding the further use of Diprovate®-G Plus Cream.

If your face skin condition has not improved after 5 days of treatment, stop using Diprovate®-G Plus Cream and seek medical advice.

For the body: Apply Diprovate®-G Plus Cream 3-4 times daily for 2 weeks. Consult your doctor regarding the further use of Diprovate®-G Plus Cream.

If your skin condition has not improved after 2 weeks of treatment, stop using Diprovate®-G Plus Cream and seek medical advice.

How to use Diprovate®-G Plus Cream:

1. Wash your hands and the affected area with mild soap or cleanser, pat dry.

2. Apply a thin layer of the cream to the affected areas.

3. Rub gently until absorbed. If desired, the treated area can be covered with gauze.

4. Wash your hands after the cream application.

Precautions

Do not stop using Diprovate®-G Plus Cream suddenly after you have noticed the improvements of your skin condition. Consult your doctor on how to gradually stop the use of Diprovate®-G Plus Cream.

Do not cover the cream application site with an occlusive bandage or synthetic covering.

Do not use Diprovate®-G Plus Cream on your face longer than 5 days.

Do not use Diprovate®-G Plus Cream on your body longer than 2 weeks.

Do not use Diprovate®-G Plus Cream more than 4 times a day.

Do not apply Diprovate®-G Plus Cream to open wounds or burns.

Patients should use sunscreens (min. SPF 15) and protective clothing while using Diprovate®-G Plus Cream.

Missing a dose

If you miss a dose you should take it as soon as you remember about your missing. If it is the time for the next dose you should continue your regular dosing schedule. Do not apply a double dose.

Overdose

Do not exceed the doctor's recommended dose. If an overdose occurs and you are feeling unwell, you should seek emergency medical attention or contact your healthcare provider immediately.

Storage

Store at a room temperature from 20 and 25 degrees C (68 and 77 degrees F) away from moisture and heat. Throw away the tube after the expiration date. Keep away from children.

Side effects

The most common side effects associated with the use of Diprovate®-G Plus Cream are:

  • allergic reactions
  • redness
  • stinging or burning sensation
  • blistering
  • peeling
  • skin rash
  • dryness of the skin
  • folliculitis
  • increased sensitivity to light
  • excessive hair growth
  • reduced skin pigmentation
  • thinning of the skin
  • red marks

Side effects occurrence does not only depend on the medication you are using, but also on your overall health and other factors.

Contraindications

Do not apply Diprovate®-G Plus Cream if you are allergic to Betamethasone Dipropionate, Gentamicin or Zinc Sulphate.

Do not apply Diprovate®-G Plus Cream if you have a history of severe allergic reactions associated with the use of glucocorticoids or antibiotics.

Do not apply Diprovate®-G Plus Cream if you are allergic to any of the other ingredients comprised in Diprovate®-G Plus Cream.

Do not use Diprovate®-G Plus Cream if you have thinning of the skin, tuberculosis, measles, a positive TB skin test, or have recently been vaccinated.

Do not use a large amount of Diprovate®-G Plus Cream continuously on large areas of the body as it may affect your hormones.

Do not use Diprovate®-G Plus Cream if you are taking painkillers (acetaminophen), alkaloids (atropine), carbonic anhydrase inhibitors (acetazolamide, methazolamide), diabetes drugs (chlorpropamide) or glucocorticoids (budesonide, cortisone, dexamethasone, hydrocortisone, methylprednisolone).

Do not use Diprovate®-G Plus Cream in patients under 13 years old.

Do not use the Diprovate®-G Plus Cream if it has already expired.

Consult your doctor if you are pregnant. Diprovate®-G Plus Cream should be used during pregnancy only if clearly needed.

Do not combine breastfeeding and Diprovate®-G Plus Cream usage without your doctor’s approval.

Frequently asked questions

Q: Can Diprovate®-G Plus Cream be used during breastfeeding?

A: You can use Diprovate®-G Plus Cream only if your doctor has instructed you to.

Q: Is Diprovate®-G Plus Cream a steroid or antibiotic drug?

A: Diprovate®-G Plus Cream is a combination treatment containing a corticosteroid and antibiotic.

Q: Can Diprovate®-G Plus Cream be used in pregnant women?

A: Diprovate®-G Plus Cream should be used during pregnancy only if potential benefits justify the potential risk. Consult your doctor before starting the treatment course.

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Reg.Mail - 14-21 business days, price - USD 20.00, no signature is required on delivery.
EMS - 5-9 business days, price - USD 30.00, signature is required on delivery.
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